Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2714015 | 0.88 | ALDH1A1 (0.43) | AAK1SSTR4L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL21078799 | 0.86 | L3MBTL1 (0.42) | AAK1SSTR4L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL15350265 | 0.86 | L3MBTL1 (0.42) | AAK1SSTR4L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL2715676 | 0.84 | L3MBTL1 (0.54) | SSTR4L3MBTL1CYP2C9CYP2C19HCAR2 | |
| SCHEMBL2714128 | 0.81 | SCN9A (0.39) | L3MBTL1CYP2C9CYP2C19GABRA5HCAR2 | |
| SCHEMBL21078750 | 0.80 | L3MBTL1 (0.40) | AAK1SSTR4L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL15350077 | 0.79 | L3MBTL1 (0.41) | L3MBTL1CYP2C9CYP2C19HCAR2KDM4E | |
| SCHEMBL15358626 | 0.78 | L3MBTL1 (0.39) | AAK1SSTR4L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL2716486 | 0.77 | MAPK1 (0.41) | AAK1SSTR4CYP2C9CYP2C19KDM4E | |
| SCHEMBL21078829 | 0.77 | CYP2C9 (0.40) | L3MBTL1CYP2C9CYP2C19GABRA5HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841421-B1 | AMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2019-06-05 | — | — | EP | disclosed |