Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15350265 | 0.91 | L3MBTL1 (0.42) | L3MBTL1SSTR4AAK1CYP2C9CYP2C19 | |
| SCHEMBL2715676 | 0.90 | L3MBTL1 (0.54) | L3MBTL1SSTR4CYP2C9CYP2C19SCN9A | |
| SCHEMBL21078902 | 0.86 | AAK1 (0.39) | L3MBTL1SSTR4AAK1CYP2C9CYP2C19 | |
| SCHEMBL21078750 | 0.85 | L3MBTL1 (0.40) | L3MBTL1SSTR4AAK1CYP2C9CYP2C19 | |
| SCHEMBL2714015 | 0.85 | ALDH1A1 (0.43) | L3MBTL1SSTR4AAK1CYP2C9CYP2C19 | |
| SCHEMBL15358626 | 0.83 | L3MBTL1 (0.39) | L3MBTL1SSTR4AAK1CYP2C9CYP2C19 | |
| SCHEMBL27150293 | 0.82 | HCAR2 (0.37) | L3MBTL1CYP2C9CYP2C19HCAR2AGBL2 | |
| SCHEMBL15350077 | 0.81 | L3MBTL1 (0.41) | L3MBTL1CYP2C9CYP2C19SCN9AHCAR2 | |
| SCHEMBL15350393 | 0.81 | SCN9A (0.54) | L3MBTL1SSTR4CYP2C9CYP2C19SCN9A | |
| SCHEMBL15350967 | 0.80 | SCN9A (0.40) | L3MBTL1CYP2C9CYP2C19SCN9AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841421-B1 | AMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2019-06-05 | — | — | EP | disclosed |