Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 9/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361821 | 0.87 | RIPK1 (0.48) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL29587495 | 0.81 | DAO (0.51) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL30759266 | 0.80 | KDM4A (0.48) | DAORIPK1 | |
| SCHEMBL1100944 | 0.79 | DAO (0.49) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL27144888 | 0.78 | DAO (0.48) | DAOPRMT5WDR77HRH4 | |
| SCHEMBL13543890 | 0.77 | RIPK1 (0.58) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL29588892 | 0.77 | RIPK1 (0.52) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL3560619 | 0.76 | IDO1 (0.58) | DAO | |
| SCHEMBL27144308 | 0.76 | NR3C1 (0.38) | — | |
| SCHEMBL5264265 | 0.75 | RIPK1 (0.46) | DAORIPK1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |