Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588892 | 0.86 | RIPK1 (0.52) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL1100944 | 0.84 | DAO (0.49) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL29602065 | 0.83 | RIPK1 (0.51) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL27151128 | 0.81 | DAO (0.49) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL5677159 | 0.80 | DAO (0.59) | DAORIPK1HRH4HRH3 | |
| SCHEMBL29419554 | 0.80 | SMN1; SMN2 (0.49) | DAORIPK1HRH4HRH3 | |
| SCHEMBL13543890 | 0.80 | RIPK1 (0.58) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL29765495 | 0.79 | RIPK1 (0.44) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL18361821 | 0.77 | RIPK1 (0.48) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL29460523 | 0.77 | RIPK1 (0.60) | DAORIPK1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685505-A | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114478528-A | Aroyl-substituted tricyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2022-05-13 | — | — | CN | disclosed |