SCHEMBL2715359

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2714541	0.91	EPHX2 (0.48)	EPHX2ADORA3PPARGPPARDPPARA
	SCHEMBL2717549	0.89	GSK3B (0.54)	ALDH1A1TSHRNPSR1MAPTGSK3A
	SCHEMBL2715322	0.89	MAPT (0.50)	EPHX2ADORA3PPARGPPARDPPARA
	SCHEMBL2716300	0.87	RIPK1 (0.52)	RIPK1ROCK2
	SCHEMBL2715999	0.84	EPHX2 (0.55)	EPHX2PPARGPPARAALDH1A1NAMPT
	SCHEMBL2715983	0.82	ROCK2 (0.58)	ROCK2ROCK1NAMPTHPGDLMNA
	SCHEMBL18266578	0.81	EPHX2 (0.44)	EPHX2RIPK1MAPTGSK3AGSK3B
	SCHEMBL2715197	0.80	NTRK1 (0.45)	EPHX2PPARGRIPK1ROCK2ROCK1
	SCHEMBL2717026	0.79	SCN10A (0.45)	EPHX2PPARGPPARAALDH1A1ROCK2
	SCHEMBL22797817	0.78	SCN9A (0.49)	PPARGPPARDPPARAGSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.