SCHEMBL2714541

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715322	0.91	MAPT (0.50)	EPHX2RIPK1ALDH1A1TSHRNPSR1
	SCHEMBL2715359	0.91	EPHX2 (0.49)	EPHX2RIPK1LMNATP53ALDH1A1
	SCHEMBL2717549	0.89	GSK3B (0.54)	ALDH1A1TSHRNPSR1MAPT
	SCHEMBL2716253	0.86	RIPK1 (0.61)	RIPK1
	SCHEMBL2715478	0.86	EPHX2 (0.48)	EPHX2RIPK1LMNATP53RXFP1
	SCHEMBL16227404	0.84	GSK3A (0.52)	LMNAALDH1A1TSHRMAPTLCLAT1
	SCHEMBL2714984	0.84	EPHX2 (0.57)	EPHX2RIPK1ALDH1A1PPARGPPARA
	SCHEMBL2714802	0.81	ROCK2 (0.60)	RIPK1ROCK2ROCK1NAMPT
	SCHEMBL18266452	0.80	RIPK1 (0.53)	RIPK1ROCK2
	SCHEMBL2715414	0.80	RIPK1 (0.52)	EPHX2RIPK1PPARGROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.