SCHEMBL2715414

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715197	0.90	NTRK1 (0.45)	RIPK1ROCK2ROCK1EPHX2HSD17B13
	SCHEMBL2717564	0.90	MAPT (0.51)	RIPK1ROCK2ROCK1EPHX2HSD17B13
	SCHEMBL2713580	0.88	GSK3B (0.50)	—
	SCHEMBL2715976	0.85	RIPK1 (0.57)	RIPK1ROCK2ROCK1EPHX2HSD17B13
	SCHEMBL2714842	0.85	GRK2 (0.55)	GRK2EPHX2PPARG
	SCHEMBL2715255	0.81	RIPK1 (0.48)	RIPK1ROCK2ROCK1CYP3A4AAK1
	SCHEMBL2716253	0.81	RIPK1 (0.61)	RIPK1
	SCHEMBL2717043	0.81	SCN3A (0.49)	RIPK1ROCK2CYP3A4AAK1
	SCHEMBL27931932	0.81	KMT2A (0.52)	ROCK2ROCK1EPHX2HSD17B13CYP3A4
	SCHEMBL2714802	0.80	ROCK2 (0.60)	RIPK1ROCK2ROCK1NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.