SCHEMBL2717564

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715414	0.90	RIPK1 (0.52)	NTRK1EPHX2ALOX5RIPK1ROCK2
	SCHEMBL2715197	0.89	NTRK1 (0.45)	NTRK1EPHX2ALOX5RIPK1ROCK2
	SCHEMBL2714691	0.86	RIPK1 (0.48)	SCN9AEPHX2ALOX5RIPK1ROCK2
	SCHEMBL2713580	0.86	GSK3B (0.50)	MAPTGSK3B
	SCHEMBL2717522	0.85	SCN9A (0.51)	MAPTGSK3BSCN9AEPHX2ALOX5
	SCHEMBL2715551	0.83	MAPT (0.51)	MAPTGSK3BSCN9ARIPK1ROCK2
	SCHEMBL2715370	0.83	MAPT (0.51)	MAPTGSK3BSCN9AROCK2KCNB1
	SCHEMBL2713250	0.82	RIPK1 (0.52)	MAPTGSK3BSCN9ARIPK1ROCK2
	SCHEMBL2715103	0.82	KCNB1 (0.60)	MAPTGSK3BSCN9ANTRK1ROCK2
	SCHEMBL2717028	0.81	MAPT (0.51)	MAPTGSK3BSCN9ANTRK1ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.