Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139330 | 0.89 | HDAC6 (0.42) | DRD2HDAC6ACKR3ALDH1A1SIGMAR1 | |
| SCHEMBL27141041 | 0.88 | DRD2 (0.40) | DRD2HDAC6ACKR3ALDH1A1SIGMAR1 | |
| SCHEMBL27148495 | 0.86 | DRD2 (0.41) | DRD2HDAC6ACKR3ALDH1A1SIGMAR1 | |
| SCHEMBL27148891 | 0.84 | DRD2 (0.46) | DRD2HDAC6ACKR3CACNA1HKDM4E | |
| SCHEMBL30782305 | 0.77 | HDAC6 (0.46) | DRD2HDAC6ALDH1A1PRSS1TMPRSS15 | |
| SCHEMBL30945677 | 0.76 | DRD2 (0.65) | DRD2ALDH1A1SIGMAR1KDM4EPOLB | |
| SCHEMBL27148065 | 0.75 | ALDH1A1 (0.49) | HDAC6ALDH1A1DAOPRSS1TMPRSS15 | |
| SCHEMBL27147160 | 0.75 | HDAC6 (0.48) | HDAC6ALDH1A1PRSS1TMPRSS15KDM4E | |
| SCHEMBL976244 | 0.75 | ADORA1 (0.55) | HDAC6ALDH1A1DAOKDM4EMAPT | |
| SCHEMBL19086993 | 0.74 | HDAC6 (0.49) | HDAC6ALDH1A1DAOSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |