Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23874038 | 0.96 | HDAC6 (0.53) | HDAC6SCDTRPV1NPBWR1MEN1 | |
| SCHEMBL27154670 | 0.85 | SCD (0.56) | HDAC6SCDTRPV1NPBWR1MEN1 | |
| SCHEMBL27154645 | 0.82 | NPC1 (0.55) | NPBWR1MEN1NPC1POLBRAB9A | |
| SCHEMBL26358087 | 0.78 | HDAC6 (0.60) | HDAC6SCDTRPV1NPBWR1MEN1 | |
| SCHEMBL23873951 | 0.76 | ESR1 (0.56) | HDAC6MEN1NPC1POLBRAB9A | |
| SCHEMBL9058427 | 0.75 | HDAC6 (0.62) | HDAC6SCDTRPV1NPBWR1MEN1 | |
| SCHEMBL26017755 | 0.75 | ESR2 (0.60) | HDAC6MEN1NPC1RAB9AKMT2A | |
| SCHEMBL12250680 | 0.75 | HDAC6 (0.61) | HDAC6SCDTRPV1NPBWR1MEN1 | |
| SCHEMBL22326618 | 0.74 | SCN10A (0.55) | HDAC6SCDTRPV1NPBWR1MEN1 | |
| SCHEMBL23874010 | 0.74 | ESR1 (0.46) | HDAC6MEN1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | PARG, PARN, NOP2 | HDAC6 380/4885SCD 2217/4885TRPV1 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.