Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.39 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27154669 | 0.96 | HDAC6 (0.52) | HDAC6TNKSTNKS2SCDTRPV1 | |
| SCHEMBL27154670 | 0.83 | SCD (0.56) | HDAC6SCDESR1ESR2GRIA1 | |
| SCHEMBL26017755 | 0.78 | ESR2 (0.60) | HDAC6ESR1ESR2GRIA1CACNG8 | |
| SCHEMBL27154645 | 0.77 | NPC1 (0.55) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL23873951 | 0.77 | ESR1 (0.56) | HDAC6ESR1ESR2GRIA1CACNG8 | |
| SCHEMBL23874010 | 0.77 | ESR1 (0.46) | HDAC6ESR1ESR2GRIA1CACNG8 | |
| SCHEMBL12250680 | 0.76 | HDAC6 (0.61) | HDAC6TNKSTNKS2SCDTRPV1 | |
| SCHEMBL14947867 | 0.74 | ESR2 (0.55) | HDAC6ESR1ESR2GRIA1CACNG8 | |
| SCHEMBL15064151 | 0.74 | ESR1 (0.58) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL19374106 | 0.74 | ESR1 (0.67) | HDAC6ESR1ESR2GRIA1CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | UNITED STATES DEPARTMENT OF ENERGY | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | PARG, PARN, NOP2 | HDAC6 360/4885TNKS 121/4885TNKS2 76/4885 |
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | PARG, PARN, NOP2 | HDAC6 380/4885TNKS 117/4885TNKS2 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.