Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925550 | 0.69 | TLR8 (0.40) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL31347845 | 0.67 | ALDH1A1 (0.33) | KDM4ELMNAHTTALDH1A1ADORA2A | |
| SCHEMBL23691650 | 0.64 | ALDH1A1 (0.43) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11727665 | 0.64 | MAPK10 (0.38) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30982511 | 0.63 | APP (0.41) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL30982652 | 0.63 | APP (0.41) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL30982501 | 0.63 | APP (0.41) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL3807141 | 0.63 | KDM4E (0.57) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL9354571 | 0.63 | APP (0.57) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL18307589 | 0.62 | CDK4 (0.52) | KDM4ELMNAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067774-A1 | PYRROLE DERIVED COMPOSITIONS AND SYTHESIS METHODS | KENNESAW STATE UNIVERSITY RESEARCH AND SERVICE FOUNDATION, INC. | 2024-02-29 | — | — | US | disclosed |
| WO-2024035888-A1 | PYRROLE DERIVED COMPOSITIONS AND SYTHESIS METHODS | KENNESAW STATE UNIVERSITY RESEARCH AND SERVICE FOUNDATION, INC. (US) | 2024-02-15 | — | — | WO | disclosed |