Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.52 |
| ▸ | CCND1 | P24385 | 4/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881998 | 0.86 | CDK4 (0.46) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL27878753 | 0.83 | LMNA (0.50) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL18856950 | 0.83 | HTR2A (0.55) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL18856947 | 0.83 | HTR2A (0.55) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL18856949 | 0.83 | HTR2A (0.55) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL14155057 | 0.83 | HTR2C (0.55) | CDK4CCND1HTR2AHTR2CTLR8 | |
| SCHEMBL111621 | 0.82 | ALDH1A1 (0.43) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL29915749 | 0.82 | ALDH1A1 (0.43) | CDK4CCND1PLGPLAUHTR2A | |
| SCHEMBL10622546 | 0.81 | OXER1 (0.51) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL18856948 | 0.81 | MTNR1A (0.58) | CDK4CCND1PLGPLAUHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118879-A1 | NOVEL DIHYDROPYRROLO[2,3-F] INDOLE-DIKETOPYRROLOPYRROLE SEMICONDUCTING MATERIALS, AND METHODS AND USES THEREOF | CORNING INCORPORATED | 2018-05-03 | — | — | US | disclosed |
| US-9896536-B2 | Dihydropyrrolo[2,3-F] indole-diketopyrrolopyrrole semiconducting materials, and methods and uses thereof | CORNING INCORPORATED (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160362517-A1 | NOVEL DIHYDROPYRROLO[2,3-F]INDOLE-DIKETOPYRROLOPYRROLE SEMICONDUCTING MATERIALS, AND METHODS AND USES THEREOF | CORNING INC (US) | 2016-12-15 | — | — | US | disclosed |
| US-20160365518-A1 | NOVEL DIHYDROPYRROLO[2,3-F] INDOLE-DIKETOPYRROLOPYRROLE SEMICONDUCTING MATERIALS, AND METHODS AND USES THEREOF | CORNING INCORPORATED | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362517-A1 | NOVEL DIHYDROPYRROLO[2,3-F]INDOLE-DIKETOPYRROLOPYRROLE SEMICONDUCTING MATERIALS, AND METHODS AND USES THEREOF | TDO2, KMO, IDO2 | CDK4 200/4885CCND1 1063/4885PLG 4490/4885 |
| US-20160365518-A1 | NOVEL DIHYDROPYRROLO[2,3-F] INDOLE-DIKETOPYRROLOPYRROLE SEMICONDUCTING MATERIALS, AND METHODS AND USES THEREOF | TDO2, KMO, IDO2 | CDK4 264/4885CCND1 1052/4885PLG 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.