SCHEMBL2715596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715595	1.00	ACACB (0.50)	ACACBROCK2ROCK1PRKACAPRKG1
	SCHEMBL2716823	0.92	GPR139 (0.52)	ACACBROCK2ROCK1PRKACAPRKG1
	SCHEMBL2713704	0.91	GSK3B (0.47)	ROCK2ROCK1PRKACAPRKG1CYP2C9
	SCHEMBL2713700	0.91	GSK3B (0.47)	ROCK2ROCK1PRKACAPRKG1CYP2C9
	SCHEMBL2716832	0.90	ACACB (0.50)	ACACBROCK2ROCK1PRKACAPRKG1
	SCHEMBL2713712	0.90	ROCK1 (0.49)	ACACBROCK2ROCK1PRKACAPRKG1
	SCHEMBL2713710	0.90	ROCK1 (0.49)	ACACBROCK2ROCK1PRKACAPRKG1
	SCHEMBL2717426	0.89	ACACB (0.56)	ACACBROCK2MAPK1MEN1LMNA
	SCHEMBL2715734	0.89	ROCK2 (0.49)	ROCK2ROCK1PRKACAPRKG1CYP2C9
	SCHEMBL2715733	0.89	ROCK2 (0.49)	ROCK2ROCK1PRKACAPRKG1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.