SCHEMBL2716832

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2716823	0.92	GPR139 (0.52)	ACACBROCK2ROCK1PRKACACYP2C9
	SCHEMBL2717140	0.91	KCNK2 (0.47)	ROCK2ROCK1PRKACACYP2C9PRKACG
	SCHEMBL2715595	0.90	ACACB (0.50)	ACACBROCK2ROCK1PRKACACYP2C9
	SCHEMBL2715596	0.90	ACACB (0.50)	ACACBROCK2ROCK1PRKACACYP2C9
	SCHEMBL2715463	0.90	ROCK1 (0.49)	ACACBROCK2ROCK1PRKACACYP2C9
	SCHEMBL2717269	0.89	ACACB (0.56)	ACACBROCK2MEN1LMNAMAPK1
	SCHEMBL2717508	0.89	ROCK2 (0.49)	ROCK2ROCK1PRKACACYP2C9PRKACG
	SCHEMBL2716778	0.86	ROCK1 (0.51)	ACACBROCK2ROCK1PRKACACYP2C9
	SCHEMBL2718076	0.86	RIPK1 (0.46)	ROCK2ROCK1PRKACACYP2C9PRKACG
	SCHEMBL18266214	0.85	ROCK1 (0.49)	ACACBROCK2ROCK1PRKACACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.