SCHEMBL27158043

SCHEMBL27158043

O=[PH](OC(C(F)(F)F)C(F)(F)F)OC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719965 0.77 CA1 (0.33) CA1CA2CA9
SCHEMBL28185747 0.77 CA1 (0.33) CA1CA2CA9
SCHEMBL17878003 0.73 ACHE (0.42)
SCHEMBL8816497 0.71
SCHEMBL8818287 0.71
SCHEMBL5015010 0.63
SCHEMBL557762 0.62
SCHEMBL10430721 0.62 CA1 (0.41) CA1CA2CA9
SCHEMBL809377 0.60 CA1 (0.38) CA1CA2CA9
SCHEMBL25834840 0.60 CA1 (0.38) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US disclosed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP disclosed
CN-115536702-A Phosphonic acid difluoro alkyl ester methylene oxygen group pentafluoro ring triphosphazene compound and its preparation 张家港市国泰华荣化工新材料有限公司 2022-12-30 CN disclosed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, CYC1, MRM1 CA1 332/4885CA2 1030/4885CA9 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.