Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068942 | 0.94 | MMP8 (0.54) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL9052677 | 0.92 | MMP8 (0.53) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL1043357 | 0.92 | ESR1 (0.55) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL490300 | 0.90 | MMP8 (0.51) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL1041533 | 0.90 | MMP8 (0.51) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL536847 | 0.90 | MMP8 (0.56) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL15030577 | 0.90 | MMP8 (0.51) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL6839623 | 0.90 | MMP8 (0.51) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL1041487 | 0.90 | LMNA (0.56) | MMP8TSHRMEN1KMT2ANPC1 | |
| SCHEMBL1772316 | 0.90 | MMP8 (0.51) | MMP8TSHRMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133997-B2 | 2,4-dioxopyrimidine-based mesoionic pigments | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20070185325-A1 | 2,4-dioxopyrimidine-based mesoionic pigments | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-08-09 | — | — | US | disclosed |
| EP-1713802-B1 | 2,4-DIOXOPYRIMIDINE-BASED MESOIONIC PIGMENTS | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2007-07-25 | — | — | EP | disclosed |