SCHEMBL6839623

SCHEMBL6839623

CCOC(=O)C(C(=O)OCC)c1ccc(CC)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.51
TSHR P16473 3/20 0.47
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
NPC1 O15118 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
RAB9A P51151 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
CA7 P43166 2/20 0.40
CA14 Q9ULX7 2/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5766034 0.91 MMP8 (0.51) MMP8TSHRALDH1A1L3MBTL1MAPK1
SCHEMBL271585 0.90 MMP8 (0.59) MMP8TSHRALDH1A1MAPK1TDP1
SCHEMBL5766030 0.89 ALDH1A1 (0.53) MMP8TSHRALDH1A1L3MBTL1MAPK1
SCHEMBL11623145 0.85 MMP8 (0.49) MMP8TSHRALDH1A1L3MBTL1NPC1
SCHEMBL27354703 0.85 MMP8 (0.49) MMP8TSHRALDH1A1NPC1MEN1
SCHEMBL6841594 0.85 MMP8 (0.49) MMP8TSHRALDH1A1L3MBTL1NPC1
SCHEMBL4068942 0.84 MMP8 (0.54) MMP8TSHRALDH1A1NPC1MEN1
SCHEMBL11646519 0.84 PTGS2 (0.54) TSHRAKR1C3AKR1C2ESR1
SCHEMBL9391853 0.84 POLB (0.49) MMP8TSHRALDH1A1NPC1MEN1
SCHEMBL8429803 0.83 AKR1C3 (0.46) TSHRALDH1A1L3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109896684-A A kind of pre-treating process for sewage in organic products preparation process 李德祥 2019-06-18 CN claimed
US-20250312504-A1 VOLATILE COMPOSITION DISPENSER FOR COMPOSITIONS COMPRISING A META-(C1-C4 ALKOXY) SALICYLALDEHYDE THE PROCTER & GAMBLE COMPANY 2025-10-09 US disclosed
US-20240199997-A1 COMPOSITIONS COMPRISING A META-(C1-C4 ALKOXY) SALICYLALDEHYDE PROCTER & GAMBLE COMPANY, THE 2024-06-20 US disclosed
CN-207862238-U A kind of Primidone reduction reaction device 精华制药集团南通有限公司 2018-09-14 CN disclosed
CN-207862237-U A kind of Primidone reduction apparatus with integrated hole flowmeter 精华制药集团南通有限公司 2018-09-14 CN disclosed
US-20180186721-A1 OXIDATIVE COUPLING OF ARYL BORON REAGENTS WITH SP3-CARBON NUCLEOPHILES, AND AMBIENT DECARBOXYLATIVE ARYLATION OF MALONATE HALF-ESTERS VIA OXIDATIVE CATALYSIS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2018-07-05 US disclosed
CN-204675849-U A kind of sewage pretreatment device for primidone synthesis JINGHUA PHARMACEUTICAL GROUP NANTONG CO LTD 2015-09-30 CN disclosed
CN-204672104-U A kind of falling film absorbing device for absorbing hydrogen sulphide waste gas JINGHUA PHARMACEUTICAL GROUP NANTONG CO LTD 2015-09-30 CN disclosed
US-6759103-B2 NEMATIC, CHOLESTERIC OR CHIRAL SMECTIC LIQUID-CRYSTAL MIXTURES HAVING HIGH ABSOLUTE DIELECTRIC ANISOTROPY VALUES AND WITH A FAVORABLE VISCOSITY/CLEARING POINT RELATIONSHIP; PHOTOSTABILITY; HEAT AND ULTRAVIOLET RADIATION RESISTANCE CLARIANT FINANCI (BVI) LIMITED (VG) 2004-07-06 US disclosed
CN-1121906-C Long-lived homogenous oxidation catalyst UNIV CARNEGIE MELLON (US) 2003-09-24 CN disclosed
US-20030091756-A1 Nematic, cholesteric or chiral smectic liquid-crystal mixtures having high absolute dielectric anisotropy values and with a favorable viscosity/clearing point relationship; photostability; heat and ultraviolet radiation resistance CLARIANT INTERNATIONAL LTD. 2003-05-15 US disclosed
CN-1230903-A Long-lived homogenous oxidation catalyst UNIV CARNEGIE MELLON (US) 1999-10-06 CN disclosed
EP-0510526-B1 Use of sulfonamides as drug and new sulfonamides HOFFMANN LA ROCHE (CH) 1996-12-04 EP disclosed
EP-0510526-A1 Use of sulfonamides as drug and new sulfonamides F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) 1992-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186721-A1 OXIDATIVE COUPLING OF ARYL BORON REAGENTS WITH SP3-CARBON NUCLEOPHILES, AND AMBIENT DECARBOXYLATIVE ARYLATION OF MALONATE HALF-ESTERS VIA OXIDATIVE CATALYSIS SOD1, AOC3, CBR3 MMP8 4481/4885TSHR 3443/4885ALDH1A1 862/4885
US-20030091756-A1 Nematic, cholesteric or chiral smectic liquid-crystal mixtures having high absolute dielectric anisotropy values and with a favorable viscosity/clearing point relationship; photostability; heat and ultraviolet radiation resistance SCO2, CNOT1, HCFC1 MMP8 3654/4885TSHR 4788/4885ALDH1A1 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.