Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27158271 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7SCN9AMRGPRX4 | |
| SCHEMBL27158707 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7SCN9AMRGPRX4 | |
| SCHEMBL29912934 | 0.85 | GPR119 (0.46) | CHRNB2CHRNA4CHRNA7SCN9ALIPE | |
| SCHEMBL27158547 | 0.82 | HDAC4 (0.37) | — | |
| SCHEMBL27158544 | 0.82 | HDAC4 (0.37) | — | |
| SCHEMBL27158488 | 0.77 | HCRTR2 (0.41) | SCN9A | |
| SCHEMBL27158611 | 0.77 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL27158608 | 0.77 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL27158666 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7MRGPRX4 | |
| Hydrochloric Acid SCHEMBL27158002 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |