Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275819 | 0.88 | NR3C2 (0.59) | NR3C2LMNATRPV4MAPTMET | |
| SCHEMBL29571805 | 0.86 | NR3C2 (1.00) | NR3C2LMNAMAPTTDP1RORC | |
| SCHEMBL1381714 | 0.86 | NR3C2 (1.00) | NR3C2LMNAMAPTTDP1RORC | |
| SCHEMBL17537607 | 0.86 | NR3C2 (0.77) | NR3C2LMNAALDH1A1ELANEMAPT | |
| SCHEMBL17493297 | 0.85 | NR3C2 (0.72) | NR3C2LMNAALDH1A1HTTELANE | |
| SCHEMBL1378883 | 0.85 | NR3C2 (0.90) | NR3C2TRPV4AVPR2GPR27PDE7A | |
| SCHEMBL1380002 | 0.84 | NR3C2 (0.88) | NR3C2TRPV4AVPR2GPR27PDE7A | |
| SCHEMBL17646149 | 0.84 | NR3C2 (0.81) | NR3C2LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL8273752 | 0.83 | NR3C2 (0.81) | NR3C2RORCAVPR2GPR27PDE7A | |
| SCHEMBL2441389 | 0.83 | NR3C2 (0.72) | NR3C2LMNAALDH1A1ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239746-A1 | PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239746-A1 | PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-07-18 | — | — | US | disclosed |
| CN-115246785-B | Process for preparing pyrrole amide compounds | 年衍药业(珠海)有限公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4332091-A1 | PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND | Sunshine Lake Pharma Co., Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022228215-A1 | PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND | 广东东阳光药业有限公司 | 2022-11-03 | — | — | WO | disclosed |
| CN-115246785-A | Process for producing pyrrole amide compound | 年衍药业(珠海)有限公司 | 2022-10-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239746-A1 | PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND | HPGDS, HRH4, FAAH | NR3C2 1528/4885LMNA 2779/4885ALDH1A1 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.