Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.77 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17493297 | 0.94 | NR3C2 (0.72) | NR3C2PDE7AHPGDELANEPTPRC | |
| SCHEMBL18950352 | 0.89 | NR3C2 (0.60) | NR3C2PDE7AHPGDPOLBELANE | |
| SCHEMBL1381714 | 0.87 | NR3C2 (1.00) | NR3C2PDE7APTPRCPDE4ALMNA | |
| SCHEMBL29571805 | 0.87 | NR3C2 (1.00) | NR3C2PDE7APTPRCPDE4ALMNA | |
| SCHEMBL27159458 | 0.86 | NR3C2 (0.76) | NR3C2PDE7APOLBELANEPTPRC | |
| SCHEMBL1378883 | 0.85 | NR3C2 (0.90) | NR3C2PDE7APTPRCPDE4AAVPR2 | |
| SCHEMBL1380002 | 0.85 | NR3C2 (0.88) | NR3C2PDE7APTPRCPDE4AAVPR2 | |
| SCHEMBL17646149 | 0.84 | NR3C2 (0.81) | NR3C2PDE7APOLBPTPRCPDE4A | |
| SCHEMBL8273752 | 0.84 | NR3C2 (0.81) | NR3C2PDE7APTPRCPDE4AAVPR2 | |
| SCHEMBL1378486 | 0.83 | NR3C2 (0.79) | NR3C2PDE7AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2985277-B1 | METHOD FOR PREPARING AN ATROPISOMER OF A PYRROLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9776961-B2 | Crystal of pyrrole derivative and method for producing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20170233341-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3190102-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2017-07-12 | — | — | EP | disclosed |
| US-9676713-B2 | Crystal of pyrrole derivative and method for producing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-06-13 | — | — | US | disclosed |
| US-9499483-B2 | Crystal of pyrrole derivative and method for producing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20160096803-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-04-07 | — | — | US | disclosed |
| EP-2985277-A1 | DIPYRROMETHENE CRYSTAL AND METHOD FOR MANUFACTURING SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096803-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | NR3C2, MC2R, CRHR1 | NR3C2 1/4885PDE7A 771/4885HPGD 1010/4885 |
| US-20170233341-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | NR3C2, MC2R, CRHR1 | NR3C2 1/4885PDE7A 771/4885HPGD 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.