Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962537 | 0.88 | GPR119 (0.37) | IDO1ENPP2ATXN2 | |
| SCHEMBL27160520 | 0.85 | TEAD1 (0.43) | NAAALIPGTEAD1 | |
| SCHEMBL27160732 | 0.81 | IDO1 (0.46) | IDO1S1PR1PRKXIKBKES1PR5 | |
| SCHEMBL19411886 | 0.80 | IDO1 (0.48) | IDO1S1PR1PRKXIKBKES1PR5 | |
| SCHEMBL21723019 | 0.74 | IDO1 (0.44) | IDO1S1PR1PRKXIKBKES1PR5 | |
| SCHEMBL27160413 | 0.74 | TEAD1 (0.50) | IDO1S1PR1PRKXIKBKES1PR5 | |
| SCHEMBL27160701 | 0.73 | ALDH1A1 (0.33) | FFAR1 | |
| SCHEMBL27160362 | 0.72 | TEAD1 (0.41) | TEAD1 | |
| SCHEMBL14668509 | 0.72 | TEAD1 (0.41) | TEAD1 | |
| SCHEMBL27160533 | 0.72 | TEAD1 (0.41) | TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4330253-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATED DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |