Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716221 | 0.89 | CNR2 (0.37) | CNR2TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL2718774 | 0.89 | CNR2 (0.43) | CNR2TRPV1DRD2DRD3TRPA1 | |
| SCHEMBL4562325 | 0.80 | TRPV1 (0.40) | TRPV1TRPA1KCNH2TRPM8HCAR2 | |
| SCHEMBL2718886 | 0.80 | CNR2 (0.40) | CNR2TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL2720162 | 0.80 | NPSR1 (0.37) | TRPV1P2RY12RBP4 | |
| SCHEMBL2384227 | 0.79 | PI4KB (0.50) | TRPV1PI4KBP2RY12HCAR2 | |
| SCHEMBL2716167 | 0.79 | GAA (0.41) | CNR2TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL2718449 | 0.79 | CNR2 (0.40) | CNR2TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL2385334 | 0.79 | PDGFRB (0.42) | KCNH2PI4KBP2RY12 | |
| SCHEMBL2384683 | 0.79 | PDGFRB (0.45) | TRPV1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |