Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715967 | 0.90 | NPSR1 (0.41) | NPSR1HSD17B10TRPV1RBP4GAA | |
| SCHEMBL2385038 | 0.81 | TRPV1 (0.48) | NPSR1HSD17B10TRPV1 | |
| SCHEMBL2716212 | 0.80 | CNR2 (0.39) | TRPV1RBP4P2RY12 | |
| SCHEMBL2383249 | 0.79 | TRPV1 (0.55) | NPSR1HSD17B10TRPV1 | |
| SCHEMBL2716221 | 0.79 | CNR2 (0.37) | HSD17B10TRPV1 | |
| SCHEMBL2381703 | 0.79 | PANK3 (0.43) | TRPV1P2RY12 | |
| SCHEMBL2716168 | 0.79 | TRPV1 (0.42) | NPSR1HSD17B10TRPV1RBP4GAA | |
| SCHEMBL2717084 | 0.79 | MEN1 (0.38) | NPSR1HSD17B10TRPV1RBP4 | |
| SCHEMBL4561884 | 0.79 | RBP4 (0.40) | TRPV1RBP4 | |
| SCHEMBL2716167 | 0.78 | GAA (0.41) | NPSR1HSD17B10TRPV1RBP4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |