Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 5/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719728 | 0.88 | MEN1 (0.40) | RBP4MEN1KMT2ATRPV1CNR2 | |
| SCHEMBL2718774 | 0.87 | CNR2 (0.43) | RBP4MEN1KMT2ATRPV1CNR2 | |
| SCHEMBL4561884 | 0.87 | RBP4 (0.40) | RBP4MEN1KMT2ATRPV1CNR2 | |
| SCHEMBL2719095 | 0.85 | PHGDH (0.49) | RBP4MEN1KMT2ATRPV1 | |
| SCHEMBL2715997 | 0.82 | KMT2A (0.38) | RBP4MEN1KMT2ATRPV1 | |
| SCHEMBL2730292 | 0.82 | TRPV1 (0.43) | RBP4MEN1KMT2ATRPV1CNR2 | |
| SCHEMBL2716178 | 0.82 | MEN1 (0.42) | RBP4MEN1KMT2ATRPV1 | |
| SCHEMBL2386385 | 0.82 | NPSR1 (0.41) | TRPV1 | |
| SCHEMBL2716556 | 0.82 | MEN1 (0.41) | RBP4MEN1KMT2ATRPV1CNR2 | |
| SCHEMBL2715957 | 0.82 | MEN1 (0.42) | RBP4MEN1KMT2ATRPV1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061337-A1 | FGFR2 MODULATORS | EXELIXIS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |