Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17130361 | 0.92 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL17130471 | 0.88 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL17130364 | 0.88 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL4011037 | 0.87 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL3346367 | 0.87 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL3347934 | 0.86 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL17130395 | 0.86 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL2716590 | 0.85 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL2716978 | 0.84 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL2717167 | 0.84 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2016-07-14 | — | — | US | claimed |
| US-9296693-B2 | Acyl piperidine inhibitors of soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-29 | — | — | US | claimed |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | claimed |
| US-10377744-B2 | Potent soluble epdxide hydrolase inhibitors | EICOSIS, LLC (US) | 2019-08-13 | — | — | US | disclosed |
| EP-2809650-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2809650-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20170174665-A1 | POTENT SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EICOSIS, LLC | 2017-06-22 | — | — | US | disclosed |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2016-07-14 | — | — | US | disclosed |
| US-9034903-B2 | Acyl piperidine inhibitors of soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-05-19 | — | — | US | disclosed |
| US-20150011586-A1 | Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase | THE REGENTS OF THE UNVERSITY OF CALIFORNIA | 2015-01-08 | — | — | US | disclosed |
| US-20150011586-A1 | Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase | THE REGENTS OF THE UNVERSITY OF CALIFORNIA | 2015-01-08 | — | — | US | disclosed |
| WO-2013116690-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-08 | — | — | WO | disclosed |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2528604-A2 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | The Regents of The University of California (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2012054093-A2 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012054093-A2 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377744-B2 | Potent soluble epdxide hydrolase inhibitors | EPHX1, EPHX2, LTA4H | EPHX2 2/4885 |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, FAAH, FAAH2 | EPHX2 4/4885 |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, FAAH, FAAH2 | EPHX2 4/4885 |
| US-20150011586-A1 | Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase | EPHX1, FAAH, FAAH2 | EPHX2 5/4885 |
| US-20170174665-A1 | POTENT SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, LTA4H | EPHX2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.