Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | CDC25B | P30305 | 4/20 | 0.52 |
| ▸ | CDC25A | P30304 | 3/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | S100A4 | P26447 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037676 | 0.86 | MEN1 (0.55) | MEN1KMT2ACDC25BCDC25AS100A4 | |
| SCHEMBL16887818 | 0.81 | MEN1 (0.56) | MEN1KMT2ACDC25BCDC25AAURKA | |
| SCHEMBL29941466 | 0.78 | CDC25B (0.68) | MEN1KMT2ACDC25BCDC25AAURKA | |
| SCHEMBL571026 | 0.78 | CDC25B (0.68) | MEN1KMT2ACDC25BCDC25AAURKA | |
| SCHEMBL6189154 | 0.77 | MAPT (0.67) | MEN1KMT2ACDC25AMAPTSMN1; SMN2 | |
| SCHEMBL9179428 | 0.77 | APAF1 (0.60) | MEN1KMT2ACDC25BS100A4MAPT | |
| SCHEMBL18182064 | 0.76 | HSP90AA1 (0.67) | MEN1KMT2AS100A4MAPTSMN1; SMN2 | |
| Water SCHEMBL8664586 | 0.76 | CDC25B (0.65) | MEN1KMT2ACDC25BCDC25AAURKA | |
| SCHEMBL11656289 | 0.75 | IDO1 (0.31) | — | |
| SCHEMBL15491792 | 0.74 | CDC25B (0.62) | MEN1KMT2ACDC25BCDC25AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11919858-B2 | Aminonapthoquinone compounds and pharmaceutical composition for blocking ubiquitination-proteasome system in diseases | CALGENT BIOTECHNOLOGY CO., LTD. (TW) | 2024-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919858-B2 | Aminonapthoquinone compounds and pharmaceutical composition for blocking ubiquitination-proteasome system in diseases | UBQLN1, PSMB1, UBQLN2 | MEN1 2805/4885KMT2A 1688/4885CDC25B 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.