Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TK1 | P04183 | 3/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663124 | 0.76 | ADRB1 (0.38) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL9751247 | 0.76 | ADRB1 (0.38) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL9634749 | 0.74 | LMNA (0.37) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL9633782 | 0.74 | LMNA (0.37) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL10533413 | 0.74 | DPP4 (0.40) | ADRB1DNMT1LMNASMN1; SMN2PNP | |
| SCHEMBL7646510 | 0.74 | PDPK1 (0.41) | ADRB1DNMT1LMNASMN1; SMN2PNP | |
| SCHEMBL1047109 | 0.74 | ADRB1 (0.33) | ADRB1DNMT1LMNASMN1; SMN2PNP | |
| SCHEMBL29673050 | 0.74 | TYRO3 (0.40) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL10702398 | 0.73 | PIM1 (0.39) | ADRB1DNMT1LMNASMN1; SMN2PNP | |
| SCHEMBL3227328 | 0.73 | PIM1 (0.39) | ADRB1DNMT1LMNASMN1; SMN2PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580635-A1 | COMBINATION THERAPIES FOR TREATMENT OF T-CELL LYMPHOMAS WITH TOLINAPANT, CEDAZURIDINE AND DECITABINE | Taiho Pharmaceutical Co., Ltd. (JP) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024047394-A1 | COMBINATION THERAPIES FOR TREATMENT OF T-CELL LYMPHOMAS WITH TOLINAPANT, CEDAZURIDINE AND DECITABINE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-03-07 | — | — | WO | disclosed |