Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30055079 | 0.85 | GPR119 (0.53) | PROKR1HSD11B1MGLLHRH3EPHX2 | |
| SCHEMBL27166133 | 0.84 | PROKR1 (0.49) | PROKR1HSD11B1MGLLEPHX2PREP | |
| SCHEMBL28392718 | 0.83 | MEN1 (0.44) | PROKR1HSD11B1MGLL | |
| SCHEMBL30055300 | 0.83 | PROKR1 (0.51) | PROKR1HSD11B1MGLLHRH3EPHX2 | |
| SCHEMBL27152941 | 0.81 | HSD11B1 (0.39) | PROKR1HSD11B1NPC1RAB9A | |
| SCHEMBL27166082 | 0.81 | EPHX2 (0.53) | PROKR1HSD11B1MGLLHRH3EPHX2 | |
| SCHEMBL27166091 | 0.81 | PROKR1 (0.49) | PROKR1HSD11B1MGLLHRH3EPHX2 | |
| SCHEMBL27166089 | 0.81 | PROKR1 (0.49) | PROKR1HSD11B1MGLLEPHX2FAAH | |
| SCHEMBL29205141 | 0.80 | PROKR1 (0.48) | PROKR1HSD11B1MGLLHRH3EPHX2 | |
| SCHEMBL2490804 | 0.80 | CHRNB2 (0.43) | PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334289-A1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | Organon R&D Finland Ltd (FI) | 2024-03-13 | — | — | EP | disclosed |