Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788172 | 0.82 | ITGB3 (0.37) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL7257968 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL6216494 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL21998060 | 0.79 | — | — | |
| SCHEMBL6775330 | 0.78 | — | — | |
| SCHEMBL1810381 | 0.78 | NR1H2 (0.33) | — | |
| SCHEMBL21997887 | 0.75 | — | — | |
| SCHEMBL18322450 | 0.75 | RIPK1 (0.34) | — | |
| SCHEMBL1206044 | 0.74 | GNAI3 (0.37) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL3586527 | 0.74 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |