Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 11/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698016 | 0.87 | MAOA (0.46) | SCN9ASCN5AKCNH2SMN1; SMN2MAOA | |
| SCHEMBL3698623 | 0.87 | MAOA (0.46) | SCN9ASCN5AKCNH2SMN1; SMN2MAOA | |
| SCHEMBL3698015 | 0.87 | MAOA (0.46) | SCN9ASCN5AKCNH2SMN1; SMN2MAOA | |
| SCHEMBL2730166 | 0.84 | GPR119 (0.45) | GPR119 | |
| SCHEMBL2728781 | 0.83 | GPR119 (0.42) | GPR119 | |
| SCHEMBL3699648 | 0.75 | MAOA (0.46) | SCN9ASCN5AKCNH2SMN1; SMN2MAOA | |
| SCHEMBL2717030 | 0.73 | GPR119 (0.40) | GPR119 | |
| SCHEMBL15234139 | 0.73 | GPR119 (0.62) | SMN1; SMN2GPR119 | |
| SCHEMBL15234082 | 0.73 | GPR119 (0.62) | SMN1; SMN2GPR119 | |
| SCHEMBL15234083 | 0.71 | GPR119 (0.42) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |