Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788590 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL12835479 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL28382554 | 0.77 | NAPRT (0.56) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL28326660 | 0.76 | NAPRT (0.54) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL13116745 | 0.76 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL9321484 | 0.76 | SMN1; SMN2 (0.68) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL4718989 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL9639987 | 0.75 | PKM (0.81) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL16217105 | 0.74 | TSHR (1.00) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL1218698 | 0.74 | TSHR (1.00) | ALDH1A1LMNAMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-06-12 | — | — | US | disclosed |
| EP-4333819-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | Katholieke Universiteit Leuven (BE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022233877-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | CNR1, CNR2, CYP2J2 | ALDH1A1 1412/4885LMNA 2454/4885MEN1 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.