Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24793341 | 1.00 | MRGPRX4 (0.48) | MRGPRX4TRPV3SMN1; SMN2TP53MAPT | |
| SCHEMBL30745366 | 0.85 | MRGPRX4 (0.49) | MRGPRX4MAPTPOLBKMT2AMEN1 | |
| SCHEMBL29826265 | 0.82 | CACNB4 (0.49) | MRGPRX4SMN1; SMN2PDE4BCNR1FNTA | |
| SCHEMBL30745369 | 0.82 | PDE4B (0.50) | MRGPRX4SMN1; SMN2TP53MAPTPDE4B | |
| SCHEMBL24793022 | 0.82 | PDE4B (0.50) | MRGPRX4SMN1; SMN2TP53MAPTPDE4B | |
| SCHEMBL30745421 | 0.82 | PDE4B (0.50) | MRGPRX4SMN1; SMN2TP53MAPTPDE4B | |
| SCHEMBL24793021 | 0.82 | PDE4B (0.50) | MRGPRX4SMN1; SMN2TP53MAPTPDE4B | |
| SCHEMBL24792598 | 0.82 | PDE4B (0.50) | MRGPRX4SMN1; SMN2TP53MAPTPDE4B | |
| SCHEMBL23554565 | 0.80 | TRPV3 (0.53) | TRPV3SMN1; SMN2MAPTPDE4BPRMT5 | |
| SCHEMBL30745352 | 0.79 | MRGPRX4 (0.48) | MRGPRX4MAPTPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334304-A1 | BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |