Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745366 | 0.83 | MRGPRX4 (0.49) | MRGPRX4ALDH1A1DPP4POLBMEN1 | |
| SCHEMBL30745393 | 0.83 | MRGPRX4 (0.47) | MRGPRX4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL30745359 | 0.81 | MRGPRX4 (0.39) | MRGPRX4ALDH1A1GPR119CYP1A2CYP2C9 | |
| SCHEMBL30745417 | 0.80 | MEN1 (0.39) | ALDH1A1POLBMEN1LMNAMAPT | |
| SCHEMBL24793341 | 0.79 | MRGPRX4 (0.48) | MRGPRX4ALDH1A1POLBRXFP1MEN1 | |
| SCHEMBL27168908 | 0.79 | MRGPRX4 (0.48) | MRGPRX4ALDH1A1POLBRXFP1MEN1 | |
| SCHEMBL30745407 | 0.79 | USP30 (0.38) | MRGPRX4ALDH1A1GPR119PTGER1 | |
| SCHEMBL30745390 | 0.78 | MRGPRX4 (0.37) | MRGPRX4ALDH1A1GPR119CYP1A2CYP2C9 | |
| SCHEMBL30745387 | 0.78 | MRGPRX4 (0.37) | MRGPRX4ALDH1A1GPR119CYP1A2CYP2C9 | |
| SCHEMBL24792024 | 0.76 | MRGPRX4 (0.49) | MRGPRX4GPR119CYP1A2CYP2C9PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |