Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717146 | 1.00 | TRPM8 (0.80) | TRPM8RECQLNPC1L3MBTL1MAPK1 | |
| SCHEMBL2718605 | 0.89 | TRPM8 (1.00) | TRPM8NPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL2718603 | 0.89 | TRPM8 (1.00) | TRPM8NPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL2717965 | 0.89 | TRPM8 (0.82) | TRPM8NPC1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL2717967 | 0.89 | TRPM8 (0.82) | TRPM8NPC1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL2720521 | 0.89 | TRPM8 (0.81) | TRPM8NPC1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL2720524 | 0.89 | TRPM8 (0.81) | TRPM8NPC1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL10168528 | 0.88 | TRPM8 (0.80) | TRPM8NPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL2721442 | 0.87 | TRPM8 (0.68) | TRPM8NPC1L3MBTL1MAPK1MAOA | |
| SCHEMBL30582839 | 0.87 | TRPM8 (0.68) | TRPM8NPC1L3MBTL1MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132323-A1 | COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT | DSM-FIRMENICH AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| EP-3470407-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-3478089-B1 | PLATED YEAST FORMULATIONS | FIRMENICH & CIE (CH) | 2021-11-03 | — | — | EP | disclosed |
| US-11160894-B2 | Perfume emanating device | FIRMENICH SA (CH) | 2021-11-02 | — | — | US | disclosed |
| US-11091734-B2 | Plated yeast formulations | FIRMENICH SA (CH) | 2021-08-17 | — | — | US | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3478089-A1 | PLATED YEAST FORMULATIONS | Firmenich SA (CH) | 2019-05-08 | — | — | EP | disclosed |
| EP-3470407-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2635572-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-10-17 | — | — | EP | disclosed |
| US-20180289704-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2018-10-11 | — | — | US | disclosed |
| US-20180264156-A1 | PERFUME EMANATING DEVICE | FIRMENICH SA (CH) | 2018-09-20 | — | — | US | disclosed |
| EP-3355944-A1 | PERFUME EMANATING DEVICE | Firmenich SA (CH) | 2018-08-08 | — | — | EP | disclosed |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | Seaomyx, Inc. (US) | 2018-07-10 | — | — | US | disclosed |
| WO-2018002331-A1 | PLATED YEAST FORMULATIONS | FIRMENICH SA (CH) | 2018-01-04 | — | — | WO | disclosed |
| US-20160317532-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2016-11-03 | — | — | US | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20130324557-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2013-12-05 | — | — | US | disclosed |
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160894-B2 | Perfume emanating device | DPM1, SURF4, FAAH2 | TRPM8 151/4885RECQL 1864/4885NPC1 1230/4885 |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885RECQL 2918/4885NPC1 1050/4885 |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885RECQL 2918/4885NPC1 1050/4885 |
| US-20180264156-A1 | PERFUME EMANATING DEVICE | DPM1, SURF4, FAAH2 | TRPM8 151/4885RECQL 1864/4885NPC1 1230/4885 |
| US-20160317532-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885RECQL 2918/4885NPC1 1050/4885 |
| US-20130324557-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885RECQL 2918/4885NPC1 1050/4885 |
| US-20180289704-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885RECQL 2918/4885NPC1 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.