Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720524 | 1.00 | TRPM8 (0.81) | TRPM8L3MBTL1NPC1KDM4EALDH1A1 | |
| SCHEMBL2718603 | 0.90 | TRPM8 (1.00) | TRPM8L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL2717965 | 0.90 | TRPM8 (0.82) | TRPM8L3MBTL1NPC1KDM4EALDH1A1 | |
| SCHEMBL2718605 | 0.90 | TRPM8 (1.00) | TRPM8L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL2717967 | 0.90 | TRPM8 (0.82) | TRPM8L3MBTL1NPC1KDM4EALDH1A1 | |
| SCHEMBL17230208 | 0.90 | TRPM8 (0.78) | TRPM8L3MBTL1NPC1KDM4E | |
| SCHEMBL10168528 | 0.89 | TRPM8 (0.80) | TRPM8L3MBTL1NPC1ALDH1A1MEN1 | |
| SCHEMBL2717146 | 0.89 | TRPM8 (0.80) | TRPM8L3MBTL1NPC1ALDH1A1MAPK1 | |
| SCHEMBL2717150 | 0.89 | TRPM8 (0.80) | TRPM8L3MBTL1NPC1ALDH1A1MAPK1 | |
| SCHEMBL2718501 | 0.87 | TRPM8 (0.77) | TRPM8KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132323-A1 | COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT | DSM-FIRMENICH AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| EP-3470407-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2024-01-24 | — | — | EP | disclosed |
| US-11234450-B2 | Preparations having a cooling effect | SYMRISE AG (DE) | 2022-02-01 | — | — | US | disclosed |
| US-11234450-B2 | Preparations having a cooling effect | SYMRISE AG (DE) | 2022-02-01 | — | — | US | disclosed |
| EP-3478089-B1 | PLATED YEAST FORMULATIONS | FIRMENICH & CIE (CH) | 2021-11-03 | — | — | EP | disclosed |
| US-11160894-B2 | Perfume emanating device | FIRMENICH SA (CH) | 2021-11-02 | — | — | US | disclosed |
| US-11091734-B2 | Plated yeast formulations | FIRMENICH SA (CH) | 2021-08-17 | — | — | US | disclosed |
| EP-2931225-B1 | COOLING PREPARATIONS | SYMRISE AG (DE) | 2021-03-31 | — | — | EP | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| EP-2931225-A1 | PREPARATIONS | Symrise AG (DE) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014090293-A1 | PREPARATIONS | SYMRISE AG (DE) | 2014-06-19 | — | — | WO | disclosed |
| US-20130324557-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2013-12-05 | — | — | US | disclosed |
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160894-B2 | Perfume emanating device | DPM1, SURF4, FAAH2 | TRPM8 151/4885L3MBTL1 4084/4885NPC1 1230/4885 |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885L3MBTL1 4024/4885NPC1 1050/4885 |
| US-11234450-B2 | Preparations having a cooling effect | CRAT, CPT2, CPT1A | TRPM8 60/4885L3MBTL1 4343/4885NPC1 1221/4885 |
| US-20130324557-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885L3MBTL1 4024/4885NPC1 1050/4885 |
| US-20150313820-A1 | PREPARATIONS | CRAT, ACAT2, TAS2R50 | TRPM8 101/4885L3MBTL1 4348/4885NPC1 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.