SCHEMBL271749

SCHEMBL271749

CCCC(C)(C)C(C)(OC(=O)c1ccccc1)OC(=O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 5/20 0.43
SLC6A3 Q01959 2/20 0.43
HTR1A P08908 1/20 0.43
SCN1A P35498 1/20 0.43
SCN5A Q14524 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
TSHR P16473 3/20 0.40
ADRB2 P07550 2/20 0.40
ADRB1 P08588 2/20 0.40
ADRB3 P13945 2/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271818 0.90 CYP2D6 (0.51) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL393485 0.82 LMNA (0.37) LMNATDP1TSHRHSD17B10
Benzoic Acid SCHEMBL11697355 0.78 LMNA (0.39) CYP2D6CYP1A2CYP2C19LMNATDP1
Octadecanoic Acid Amide SCHEMBL8002943 0.78 CES2 (0.46) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL23532587 0.75 LMNA (0.53) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL12394143 0.75 CYP2D6 (0.54) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL28035570 0.75 CYP2D6 (0.54) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL1784682 0.72 CYP2D6 (0.49) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL13514895 0.71 CYP2D6 (0.76) CYP2D6CYP1A2CYP2C19LMNATDP1
SCHEMBL1785119 0.71 CYP2D6 (0.50) CYP2D6CYP1A2CYP2C19LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442951-B2 Water dispersible, self-crosslinkable prepolymer composition LUBRIZOL ADVANCED MATERIALS, INC. (US) 2019-10-15 US disclosed
EP-2235077-B2 USE OF A WATERBORNE COMPOSITION AS A WATERBORNE COATING WITH IMPROVED EARLY WATER BLUSHING AND CHEMICAL RESISTANCE LUBRIZOL ADVANCED MAT INC (US) 2017-06-21 EP disclosed
US-20170145245-A1 WATER DISPERSIBLE, SELF-CROSSLINKABLE PREPOLYMER COMPOSITION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-05-25 US disclosed
US-9567311-B2 Water dispersible, self-crosslinkable prepolymer composition LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-02-14 US disclosed
EP-2807207-B1 WATER DISPERSIBLE, SELF-CROSSLINKABLE PREPOLYMER COMPOSITION LUBRIZOL ADVANCED MAT INC (US) 2016-12-28 EP disclosed
WO-2016153818-A1 BLENDS OF WATER DISPERSIBLE POLYMER WITH DISPERSIONS OF POLYMERS FROM EPOXIDIZED TRIGLYCERIDES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-09-29 WO disclosed
US-20140378607-A1 WATER DISPERSIBLE, SELF-CROSSLINKABLE PREPOLYMER COMPOSITON LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-12-25 US disclosed
EP-2235077-B1 WATERBORNE COATINGS WITH IMPROVED EARLY WATER BLUSHING AND CHEMICAL RESISTANCE LUBRIZOL ADVANCED MAT INC (US) 2014-03-19 EP disclosed
US-8133961-B2 Waterborne coatings with improved early water blushing and chemical resistance LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-03-13 US disclosed
EP-2235077-A2 WATERBORNE COATINGS WITH IMPROVED EARLY WATER BLUSHING AND CHEMICAL RESISTANCE Lubrizol Advanced Materials, Inc. (US) 2010-10-06 EP disclosed
EP-0501272-A1 Latex for coatings having improved flexibility THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-09-02 EP disclosed
US-5122566-A Free radical emulsion polymerization of monomer mixture, neutralizaton with ammonia THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-06-16 US disclosed
EP-0476528-A2 Process for producing stable latex THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-25 EP disclosed
EP-0421909-A2 Latex for coatings having reduced blushing characteristics THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-04-10 EP disclosed
US-4968741-A PROTECTIVE COATINGS FOR METALS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-11-06 US disclosed
US-4189561-A FREE RADICAL EMULSION POLYMERIZED; HYDROPHOBIC AND HYDROPHILIC MONOMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-02-19 US disclosed
US-4153592-A HYDROPHOBIC-HYDROPHILIC ADDITION INTERPOLYMER, AMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-05-08 US disclosed
US-4124555-A FILM FORMING THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-11-07 US disclosed
US-4097440-A PAINTS, ADDITION POLYMERS, PLASTICIZERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-27 US disclosed
US-4064092-A ADDITION POLYMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378607-A1 WATER DISPERSIBLE, SELF-CROSSLINKABLE PREPOLYMER COMPOSITON COASY, ABHD6, HACL2 CYP2D6 1339/4885CYP1A2 306/4885CYP2C19 1405/4885
US-10442951-B2 Water dispersible, self-crosslinkable prepolymer composition ABHD6, COASY, HACL2 CYP2D6 1289/4885CYP1A2 457/4885CYP2C19 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.