Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.78 |
| ▸ | RAB9A | P51151 | 6/20 | 0.78 |
| ▸ | HTT | P42858 | 5/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.73 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.70 |
| ▸ | MITF | O75030 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15741850 | 1.00 | AGTR1 (1.00) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL1028452 | 0.95 | AGTR1 (0.91) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL12720823 | 0.94 | AGTR1 (0.88) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL1025581 | 0.86 | AGTR1 (0.76) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL1028098 | 0.85 | AGTR1 (0.74) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL12720819 | 0.84 | AGTR1 (0.71) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL1024477 | 0.84 | AGTR1 (0.72) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL12720802 | 0.83 | AGTR1 (0.71) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL31690656 | 0.83 | AGTR1 (0.70) | AGTR1SMN1; SMN2RAB9AHTTLMNA | |
| SCHEMBL1562723 | 0.81 | GSTA1 (0.68) | AGTR1SMN1; SMN2RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580403-A2 | APYRASE INHIBITORS | Texas Crop Science, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| US-20240101510-A1 | APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | claimed |
| WO-2024050040-A2 | APYRASE INHIBITORS | TEXAS CROP SCIENCE (US) | 2024-03-07 | — | — | WO | claimed |
| US-20240101510-A1 | APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101510-A1 | APYRASE INHIBITORS | APEH, DPEP1, PON1 | AGTR1 865/4885SMN1; SMN2 4511/4885RAB9A 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.