SCHEMBL27182931

SCHEMBL27182931

COC(=O)CCNC(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.65
▸ HTT P42858 1/20 0.65
▸ ALDH1A1 P00352 2/20 0.62
▸ KMT2A Q03164 8/20 0.60
▸ MEN1 O00255 7/20 0.60
▸ MAPT P10636 3/20 0.60
▸ SMN1; SMN2 Q16637 2/20 0.60
▸ CNR1 P21554 1/20 0.57
▸ NPC1 O15118 2/20 0.55
▸ MAPK1 P28482 2/20 0.55
▸ RAB9A P51151 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ MYOC Q99972 1/20 0.55
▸ LMNA P02545 2/20 0.54
▸ PABPC1 P11940 1/20 0.52
▸ CA12 O43570 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA4 P22748 1/20 0.52
▸ CA7 P43166 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30834839 0.84 POLB (0.56) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL27182713 0.84 POLB (0.66) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL29363197 0.83 POLB (0.64) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL6907398 0.82 POLB (0.72) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL27923049 0.81 POLB (0.70) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL5478291 0.81 POLB (0.69) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL11745025 0.80 POLB (0.68) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL10805170 0.80 POLB (0.68) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL10804640 0.79 POLB (0.74) POLBHTTALDH1A1KMT2AMEN1
SCHEMBL7915467 0.79 POLB (1.00) POLBHTTALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 — — US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 — — EP disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 — — WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL POLB 4105/4885HTT 1286/4885ALDH1A1 4390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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