SCHEMBL27184

SCHEMBL27184

C=CC=CC(C=Cc1ccccc1)=C(C=CC=C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 6/20 0.44
MAPT P10636 4/20 0.44
MAOB P27338 4/20 0.44
PLIN1 O60240 2/20 0.44
LMNA P02545 2/20 0.44
RECQL P46063 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
BCHE P06276 1/20 0.44
TNFRSF1A P19438 1/20 0.44
ACHE P22303 1/20 0.44
HDAC3 O15379 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
F3 P13726 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146781 0.97 CYP1B1 (0.44) CYP1B1MAPTMAOBPLIN1LMNA
Styrene SCHEMBL1946755 0.95 ALDH1A1 (0.42) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL1003800 0.95 CYP1B1 (0.46) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL1686029 0.92 CYP1B1 (0.43) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL4657359 0.90 HDAC3 (0.50) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL16147696 0.90 HDAC3 (0.50) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL18833161 0.89 AKT1 (0.39) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL3939691 0.89 MAPT (0.43) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL461687 0.84 MAPT (0.37) CYP1B1MAPTMAOBPLIN1LMNA
SCHEMBL5671693 0.84 CYP1B1 (0.55) CYP1B1MAPTMAOBPLIN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113329891-B Rubber composition and tire 住友橡胶工业株式会社 2024-02-09 CN claimed
US-20230202236-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-06-29 US claimed
EP-4155095-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2023-03-29 EP claimed
CN-114867619-B Tyre 住友橡胶工业株式会社 2023-01-31 CN claimed
CN-114867619-A Tyre for vehicle wheels 住友橡胶工业株式会社 2022-08-05 CN claimed
CN-112662043-A Preparation and implementation method of impact force protection foaming shoe material 郑忠利 2021-04-16 CN claimed
US-8729169-B2 Synthetic rubber with anti-oxidants for rubber KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2014-05-20 US claimed
EP-2064285-B1 BULK LIGHT DIFFUSER COMPOSITION USI CORP (TW) 2013-10-23 EP claimed
EP-1827819-B1 HIGH PERFORMANCE ELASTIC MATERIALS MADE USING STYRENE BLOCK COPOLYMERS AND MIXTURES KIMBERLY CLARK CO (US) 2013-05-22 EP claimed
US-20120270982-A1 ANTI-OXIDANTS FOR RUBBER AND SYNTHETIC RUBBER WITH THEREOF KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-10-25 US claimed
US-20100067258-A1 BULK LIGHT DIFFUSER COMPOSITION USI CORPORATION (TW) 2010-03-18 US claimed
US-7651783-B2 Surface treated copper film NIKKO MATERIALS CO., LTD. (JP) 2010-01-26 US claimed
EP-1799765-B1 COMBINATIONS OF TACKIFIER AND POLYALPHAOLEFIN OIL EXXONMOBIL CHEM PATENTS INC (US) 2010-01-13 EP claimed
US-7612001-B2 High performance elastic materials made using styrene block copolymers and mixtures KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-11-03 US claimed
EP-2064285-A1 BULK LIGHT DIFFUSER COMPOSITION Dow Global Technologies Inc. (US) 2009-06-03 EP claimed
WO-2008045181-A1 BULK LIGHT DIFFUSER COMPOSITION DOW GLOBAL TECHNOLOGIES INC. (US) 2008-04-17 WO claimed
EP-1827819-A1 HIGH PERFORMANCE ELASTIC MATERIALS MADE USING STYRENE BLOCK COPOLYMERS AND MIXTURES Kimberly-Clark Worldwide, Inc. (US) 2007-09-05 EP claimed
WO-2006071321-A1 HIGH PERFORMANCE ELASTIC MATERIALS MADE USING STYRENE BLOCK COPOLYMERS AND MIXTURES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2006-07-06 WO claimed
US-20060135024-A1 High performance elastic materials made using styrene block copolymers and mixtures KIMBERLY-CLARK WORLDWIDE, INC. 2006-06-22 US claimed
EP-0387662-A2 Polynorbornene machinable stock and machined product NIPPON ZEON CO., LTD. (JP) 1990-09-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120270982-A1 ANTI-OXIDANTS FOR RUBBER AND SYNTHETIC RUBBER WITH THEREOF TST, GPX4, PRDX3 CYP1B1 1060/4885MAPT 3815/4885MAOB 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.