Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347459 | 0.88 | CA2 (0.47) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL10304982 | 0.88 | — | — | |
| SCHEMBL25516 | 0.88 | — | — | |
| SCHEMBL10305019 | 0.88 | — | — | |
| SCHEMBL192696 | 0.84 | CA2 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL26940441 | 0.84 | CA2 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2137285 | 0.82 | GPR84 (0.52) | CA2MAPK1GPR84FFAR1MAPT | |
| Hexanoate SCHEMBL935031 | 0.81 | AKR1B1 (0.57) | TDP1ALDH1A1TSHRNPSR1GPR84 | |
| SCHEMBL3858716 | 0.80 | GPR84 (0.55) | CA2GPR84FFAR1MAPTLCK | |
| SCHEMBL2553409 | 0.80 | GPR84 (0.55) | CA2GPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514744-A1 | Novel compounds and compositions thereof | Lubrizol Limited (GB) | 2012-10-24 | — | — | EP | disclosed |
| EP-2064179-B1 | DISPERSANTS CONTAINING TERMINAL ACIDIC GROUPS | LUBRIZOL LTD (GB) | 2012-08-29 | — | — | EP | disclosed |
| US-20120165385-A1 | Novel Compounds And Compositions Thereof | LUBRIZOL LIMITED (GB) | 2012-06-28 | — | — | US | disclosed |
| EP-2463275-A1 | Novel compounds and compositions thereof | Lubrizol Limited (GB) | 2012-06-13 | — | — | EP | disclosed |
| US-8133914-B2 | Compounds and compositions thereof | LUBRIZOL LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100035958-A1 | Novel Compounds And Compositions Thereof | LUBRIZOL LIMITED (GB) | 2010-02-11 | — | — | US | disclosed |
| EP-2064179-A2 | NOVEL COMPOUNDS AND COMPOSITIONS THEREOF | Lubrizol Limited (GB) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008028954-A2 | NOVEL COMPOUNDS AND COMPOSITIONS THEREOF | LUBRIZOL LIMITED (GB) | 2008-03-13 | — | — | WO | disclosed |
| EP-1088018-A1 | ETHER/ESTER DISPERSANTS | Avecia Limited (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1080127-A1 | AMINE DISPERSANTS | Avecia Limited (GB) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999055763-A1 | AMINE DISPERSANTS | AVECIA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999055762-A1 | ETHER/ESTER DISPERSANTS | AVECIA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165385-A1 | Novel Compounds And Compositions Thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCL11, C5 | CHRM1 679/4885AKR1A1 4074/4885CHRM3 62/4885 |
| US-20100035958-A1 | Novel Compounds And Compositions Thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCL11, C5 | CHRM1 679/4885AKR1A1 4074/4885CHRM3 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.