SCHEMBL12374598

SCHEMBL12374598

BC1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.53
P2RY2 P41231 18/20 0.50
P2RY4 P51582 3/20 0.50
P2RX3 P56373 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14406690 1.00 FBP1 (0.53) FBP1P2RY2P2RY4P2RX3
SCHEMBL24454421 0.97 FBP1 (0.56) FBP1P2RY2P2RY4
SCHEMBL13574842 0.95 FBP1 (0.53) FBP1P2RY2P2RY4P2RX3
SCHEMBL17732505 0.87 P2RY2 (0.45) FBP1P2RY2P2RY4
SCHEMBL13588383 0.87 FBP1 (0.45) FBP1P2RY2P2RY4
SCHEMBL14072553 0.85 FBP1 (0.49) FBP1P2RY2P2RY4P2RX3
SCHEMBL9945522 0.85 P2RY2 (0.45) FBP1P2RY2P2RY4
SCHEMBL3411522 0.84 FBP1 (0.56) FBP1P2RY2P2RY4
SCHEMBL1469765 0.84 FBP1 (0.56) FBP1P2RY2P2RY4
SCHEMBL30748277 0.84 FBP1 (0.56) FBP1P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003769-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2011-08-23 US disclosed
US-8003769-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2011-08-23 US disclosed
US-20100292457-A1 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-11-18 US disclosed
US-20100292457-A1 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-11-18 US disclosed
US-7678892-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-03-16 US disclosed
US-7678892-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-03-16 US disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 US disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 US disclosed
US-20070254298-A1 ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) 2007-11-01 US disclosed
US-20070254298-A1 ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) 2007-11-01 US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292457-A1 Dye-labeled ribonucleotide triphosphates DUT, POLRMT, SAMHD1 FBP1 1156/4885P2RY2 806/4885P2RY4 431/4885
US-20070254298-A1 ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS CHRNB3, CHRNB4, SPR FBP1 387/4885P2RY2 3565/4885P2RY4 3008/4885
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates DUT, POLRMT, SAMHD1 FBP1 1156/4885P2RY2 806/4885P2RY4 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.