Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669748 | 0.94 | KCNH2 (0.42) | POLBRECQLMAPTALDH1A1HTT | |
| SCHEMBL9728301 | 0.83 | ALDH1A1 (0.42) | POLBRECQLMAPTALDH1A1HTT | |
| SCHEMBL10669167 | 0.75 | POLB (0.42) | POLBRECQLMAPTL3MBTL1KCNH2 | |
| SCHEMBL10665061 | 0.75 | POLB (0.42) | POLBRECQLMAPTALDH1A1HTT | |
| SCHEMBL10668219 | 0.71 | MAPT (0.42) | POLBRECQLMAPTALDH1A1GAA | |
| SCHEMBL24767235 | 0.71 | ALDH1A1 (0.37) | POLBMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL6827112 | 0.70 | GAA (0.41) | POLBMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL10223485 | 0.69 | GAA (0.40) | POLBMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL8635202 | 0.68 | ALDH1A1 (0.57) | POLBMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL6087379 | 0.68 | FFAR1 (0.47) | MAPTALDH1A1KCNH2TNK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349834-A1 | BENZIMIDAZOLE COMPOUND OR SALT THEREOF, DIROFILARIASIS CONTROL AGENT CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | Nihon Nohyaku Co., Ltd. (JP) | 2024-04-10 | — | — | EP | disclosed |
| CN-117412963-A | Benzimidazole compound or salt thereof, heartworm disease preventing and treating agent containing the same, and method for using the same | 日本农药株式会社 | 2024-01-16 | — | — | CN | disclosed |