Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223485 | 0.76 | GAA (0.40) | GAAALDH1A1L3MBTL1HTTTSHR | |
| SCHEMBL14230737 | 0.76 | GAA (0.40) | GAAALDH1A1L3MBTL1HTTTSHR | |
| SCHEMBL1252899 | 0.74 | ERN1 (0.47) | — | |
| SCHEMBL2110165 | 0.73 | CA12 (0.40) | GAAALDH1A1L3MBTL1HTTTSHR | |
| SCHEMBL2109624 | 0.72 | KDM4E (0.47) | GAAALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL22797136 | 0.72 | ALDH1A1 (0.36) | GAAALDH1A1L3MBTL1HTTTSHR | |
| SCHEMBL2305122 | 0.71 | — | — | |
| SCHEMBL9227451 | 0.71 | — | — | |
| SCHEMBL27190897 | 0.70 | POLB (0.43) | GAAALDH1A1L3MBTL1HTTTSHR | |
| SCHEMBL2108733 | 0.70 | FFAR1 (0.38) | GAAALDH1A1L3MBTL1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051314-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | PARIS SCIENCES ET LETTRES (FR) | 2025-02-13 | — | — | US | disclosed |
| EP-4444308-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | Institut Curie (FR) | 2024-10-16 | — | — | EP | disclosed |
| CN-112074507-B | Compounds as Antibiotics | 山东亨利医药科技有限责任公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023104976-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | INSTITUT CURIE (FR) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023104976-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | INSTITUT CURIE (FR) | 2023-06-15 | — | — | WO | disclosed |
| US-20200392096-A1 | COMPOUND ACTING AS ANTIBIOTICS | KBP BIOSCIENCES CO., LTD. (CN) | 2020-12-17 | — | — | US | disclosed |
| EP-3750881-A1 | COMPOUND ACTING AS ANTIBIOTICS | KBP Biosciences Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |
| CN-112074507-A | Compounds as antibiotics | 山东亨利医药科技有限责任公司 | 2020-12-11 | — | — | CN | disclosed |
| WO-2019154412-A1 | COMPOUND ACTING AS ANTIBIOTICS | 山东亨利医药科技有限责任公司 | 2019-08-15 | — | — | WO | disclosed |
| CN-104744446-A | Hetero-aromatic compound and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2015-07-01 | — | — | CN | disclosed |
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392096-A1 | COMPOUND ACTING AS ANTIBIOTICS | PEPD, NRDC, DPP4 | GAA 273/4885ALDH1A1 1492/4885L3MBTL1 2656/4885 |
| US-20250051314-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | STAT1, IFNG, IRF2BP2 | GAA 786/4885ALDH1A1 4394/4885L3MBTL1 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.