Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669748 | 0.83 | KCNH2 (0.42) | ALDH1A1TSHRMAPTKDM4ECYP3A4 | |
| SCHEMBL27190897 | 0.83 | POLB (0.43) | ALDH1A1TSHRMAPTKDM4ECYP1A2 | |
| SCHEMBL10921009 | 0.69 | ALDH1A1 (0.66) | ALDH1A1TSHRMAPTKDM4EPOLB | |
| SCHEMBL31353026 | 0.67 | ALDH1A1 (0.68) | ALDH1A1TSHRMAPTKDM4ECYP3A4 | |
| SCHEMBL31353027 | 0.67 | ALDH1A1 (0.68) | ALDH1A1TSHRMAPTKDM4ECYP3A4 | |
| SCHEMBL9119911 | 0.67 | CYP3A4 (0.59) | ALDH1A1TSHRMAPTKDM4ECYP1A2 | |
| SCHEMBL6827112 | 0.66 | GAA (0.41) | ALDH1A1TSHRMAPTKDM4ECYP3A4 | |
| SCHEMBL18452361 | 0.66 | KDM4E (0.53) | ALDH1A1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL22797136 | 0.65 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4ECYP3A4CYP2C9 | |
| SCHEMBL10223485 | 0.65 | GAA (0.40) | ALDH1A1TSHRMAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116981-A | Antiinflammatory leukotriene B4 analogs | THE UPJOHN COMPANY (US) | 1992-05-26 | — | — | US | disclosed |