Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27193306 | 0.84 | NPC1 (0.47) | PTPN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL25491824 | 0.79 | RAB9A (0.88) | PTPN1NPC1RAB9ADEGS1MEN1 | |
| SCHEMBL17066707 | 0.79 | RAB9A (0.88) | PTPN1NPC1RAB9ADEGS1MEN1 | |
| SCHEMBL25970267 | 0.79 | RAB9A (0.88) | PTPN1NPC1RAB9ADEGS1MEN1 | |
| SCHEMBL15214314 | 0.79 | RAB9A (0.88) | PTPN1NPC1RAB9ADEGS1MEN1 | |
| SCHEMBL27193265 | 0.79 | P4HTM (0.56) | PTPN1NPC1RAB9AMEN1KMT2A | |
| Benzidine SCHEMBL22206777 | 0.78 | POLB (0.85) | PTPN1NPC1RAB9ADEGS1POLB | |
| SCHEMBL16592197 | 0.77 | PTPN1 (0.75) | PTPN1NPC1RAB9ADEGS1POLB | |
| SCHEMBL20284045 | 0.77 | DEGS1 (0.86) | PTPN1NPC1RAB9ADEGS1POLB | |
| SCHEMBL25141374 | 0.76 | POLB (0.88) | PTPN1NPC1RAB9ADEGS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | PTPN1 937/4885NPC1 2211/4885RAB9A 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.