Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27193298 | 0.84 | PTPN1 (0.61) | NPC1RAB9ATRPV1KMT2APTPN1 | |
| SCHEMBL27193296 | 0.81 | HTR1D (0.43) | NPC1RAB9ATRPV1KMT2AMAPK14 | |
| SCHEMBL30828558 | 0.81 | KCNK3 (0.55) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL22580645 | 0.75 | NPC1 (0.66) | NPC1RAB9AKMT2APTPN1SMN1; SMN2 | |
| SCHEMBL22580585 | 0.75 | NPC1 (0.66) | NPC1RAB9AKMT2APTPN1SMN1; SMN2 | |
| SCHEMBL30828560 | 0.74 | MAPK14 (0.45) | NPC1RAB9ATRPV1MAPK14HTR1D | |
| SCHEMBL25815389 | 0.72 | NPC1 (0.72) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL13400967 | 0.72 | RAB9A (0.67) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL27193249 | 0.71 | RAB9A (0.54) | NPC1RAB9ATRPV1KMT2APTPN1 | |
| SCHEMBL14285959 | 0.71 | PTPN1 (0.69) | NPC1RAB9AKMT2AMAPK14PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | NPC1 2211/4885RAB9A 1510/4885TRPV1 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.