SCHEMBL30863469

SCHEMBL30863469

COc1cc(OCCN(C)C)ccc1C(=O)Nc1cccc2ncccc12

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ MEN1 O00255 4/20 0.56
▸ KMT2A Q03164 4/20 0.56
▸ RECQL P46063 1/20 0.52
▸ THRB P10828 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.49
▸ CLK1 P49759 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ PABPC1 P11940 2/20 0.47
▸ EIF4H Q15056 2/20 0.47
▸ KDR P35968 1/20 0.47
▸ POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863494 0.89 MEN1 (0.57) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL27195715 0.89 MEN1 (0.57) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL30863532 0.87 MEN1 (0.54) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL27195700 0.87 MEN1 (0.54) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL27195697 0.83 SMN1; SMN2 (0.67) MAPTSMN1; SMN2HSD17B10L3MBTL1MEN1
SCHEMBL30806836 0.81 PABPC1 (0.54) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL30807071 0.77 RXFP1 (0.53) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL1353280 0.72 MAPT (0.74) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL7502761 0.71 MEN1 (0.65) MAPTKDM4ESMN1; SMN2HSD17B10L3MBTL1
SCHEMBL27195737 0.70 KMT2A (0.56) MAPTKDM4ESMN1; SMN2HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
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