SCHEMBL30863532

SCHEMBL30863532

CN(C)CCOc1ccc(C(=O)Nc2cccc3ncccc23)c(C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.54
▸ KMT2A Q03164 5/20 0.54
▸ MAPT P10636 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ CLK1 P49759 1/20 0.47
▸ PABPC1 P11940 3/20 0.46
▸ EIF4H Q15056 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ THRA P10827 1/20 0.46
▸ THRB P10828 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ CYP1A2 P05177 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ RXFP1 Q9HBX9 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ NPY5R Q15761 1/20 0.44
▸ POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27195700 1.00 MEN1 (0.54) MEN1KMT2AMAPTKDM4ECLK1
SCHEMBL30863469 0.87 MAPT (0.58) MEN1KMT2AMAPTKDM4ECLK1
SCHEMBL27195715 0.87 MEN1 (0.57) MEN1KMT2AMAPTKDM4ECLK1
SCHEMBL30863494 0.87 MEN1 (0.57) MEN1KMT2AMAPTKDM4ECLK1
SCHEMBL27195697 0.81 SMN1; SMN2 (0.67) MEN1KMT2AMAPTCLK1PABPC1
SCHEMBL30807071 0.81 RXFP1 (0.53) MEN1KMT2AMAPTKDM4ECLK1
SCHEMBL30806836 0.77 PABPC1 (0.54) MEN1KMT2AMAPTKDM4ECLK1
SCHEMBL27195874 0.74 THRA (0.63) KDM4ESMN1; SMN2THRATHRBPOLB
SCHEMBL27195871 0.73 THRA (0.60) KDM4ESMN1; SMN2THRATHRBPOLB
SCHEMBL27195922 0.72 THRA (0.61) KDM4ETHRATHRBCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
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