Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | LCAT | P04180 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484365 | 1.00 | ADRA2A (0.44) | ADRA2ADRD1DRD5ADRA1BP2RY14 | |
| SCHEMBL22688514 | 0.80 | P2RY14 (0.57) | ADRA2ADRD1DRD5ADRA1BP2RY14 | |
| SCHEMBL21381864 | 0.79 | HDAC4 (0.47) | DRD1DRD5P2RY14HDAC4CYP11B1 | |
| SCHEMBL28818474 | 0.78 | DRD2 (0.59) | ADRA2ADRD1DRD5ADRA1BP2RY14 | |
| SCHEMBL29202381 | 0.77 | TP53 (0.39) | — | |
| SCHEMBL13210515 | 0.74 | HTR2C (0.62) | ADRA2ADRD1DRD5ADRA1BP2RY14 | |
| SCHEMBL13210513 | 0.73 | P2RY14 (0.52) | P2RY14 | |
| SCHEMBL20744371 | 0.73 | EPHX2 (0.51) | — | |
| SCHEMBL30305368 | 0.73 | EPHX2 (0.51) | — | |
| Hydrochloric Acid SCHEMBL21381772 | 0.73 | HTR2C (0.63) | DRD1DRD5ADRA1BP2RY14SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124429-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2024-04-18 | — | — | US | claimed |
| WO-2024024962-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC RING DERIVATIVE | 住友ファーマ株式会社 | 2024-02-01 | — | — | WO | claimed |
| US-20240124429-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2024-04-18 | — | — | US | disclosed |
| WO-2024024962-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC RING DERIVATIVE | 住友ファーマ株式会社 | 2024-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124429-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE | H1-0, HTT, PRNP | ADRA2A 3214/4885DRD1 382/4885DRD5 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.